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Nonlinear Dynamics and Bifurcation in the Hoff Model of Oscillations of a Microbubble Contrast Agent

Student: Tyuteva Anastasiya

Supervisor: Dmitry Sinelshchikov

Faculty: HSE Tikhonov Moscow Institute of Electronics and Mathematics (MIEM HSE)

Educational Programme: Applied Mathematics (Bachelor)

Year of Graduation: 2021

The main object of the study is a microbubble contrast agent that is injected into the circulatory system. For extended use in medicine, it is necessary to have an understanding of the behavior of nonlinear dynamics and emerging states. In the course of the work, the model of a microbubble contrast agent in the Hoff's model was considered, which had not been studied earlier. To study the dynamics, programs were developed that allow one to build phase portraits, Poincaré sections and bifurcation diagrams; the senior Lyapunov exponent is also calculated. A study on the emergence of a state of multistability in the system was carried out. The results of this work can be useful in medicine for ultrasound diagnostics and in other applications.

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