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Regular version of the site

Open lecture “Neuroscience and neurorehabilitation of language: Theory – Experiment - Translation” by Professor Friedemann Pulvermüller

We are pleased to invite you to “Neuroscience and neurorehabilitation of language: Theory – Experiment - Translation”, open lecture by Friedemann Pulvermüller on Febraury, 9th at 5 pm.

Open lecture “Neuroscience and neurorehabilitation of language: Theory – Experiment - Translation” by Professor Friedemann Pulvermüller

We would like to invite you to “Neuroscience and neurorehabilitation of language: Theory – Experiment - Translation”, open lecture by Friedemann Pulvermüller, one of the world’s foremost experts in the neurobiology of speech and languageFriedemann Pulvermüller is a professor in the Neuroscience of Language and Pragmatics at Freie Universität Berlin, Germany, Head of Brain Language Laboratory, Honorary Professor at University of Plymouth, University of Helsinki and University of Malaga. Professor Pulvermüller  is one of the main proponents of embodied cognition, author of more than 250 scientific articles (H-index - 66).

The open lecture will take place in room 423 on Myasnitskaya street, 9/11 on February, 9th at 5 pm.

If you don’t have a pass to HSE, contact Irina Badusheva ( irina.baduseva@gmail.com, mob. +7 (977) 427-43-81).

Working language is English.

ABSTRACT: Advances in theoretical and experimental neuroscience have important implications for clinical practice. Brain research documented that the cortical mechanisms for language and action are tightly interwoven and, concurrently, new approaches to language therapy in neurological patients are being developed that implement language training in the context of relevant linguistic and non-linguistic actions, therefore taking advantage of the mutual connections of language and action systems in the brain. A further well-known neuroscience principle is that learning at the neuronal level is driven by correlation of neural activity; consequently, new approaches to language therapy emphasize massed practice in a short time, thus maximizing therapy quantity and frequency and, therefore, correlation at the behavioral and neuronal levels. Learned nonuse of unsuccessful actions plays a major role in the chronification of neurological deficits and behavioral approaches to therapy have therefore employed shaping and other learning techniques to counteract such nonuse. These insights from neuroscience combine to yield a new kind of therapy approach to post-stroke aphasia, called constraint-induced aphasia therapy or intensive language-action therapy (ILAT).

Whereas classical wisdom had been that post-stroke aphasia cannot be significantly improved at a chronic stage, a short intensive training interval (2 weeks, 2 hours/day) of ILAT yields significant improvement of language performance in patients with chronic aphasia, several years after their stroke. The method has recently been improved further by applying drug treatment in conjunction with the behavioral training. ILAT now appears as an efficient tool for improving language functions, even at chronic stages of aphasia. In future, we will aim to further optimize the method, strive to understand its underlying mechanisms and explore its perspectives with regard to a spectrum of communicative and cognitive deficits. My talk will focus on recent advances achieved with regard to the question which specific features of ILAT contribute to its effectiveness.

As a further benefit, ILAT as a rapid effective technique for language therapy in chronic post-stroke aphasia provides a unique tool for exploring the cortical reorganization of language independent of any spontaneous restitution processes. Therefore, therapy studies using this technique can open new perspectives for research into the plasticity of human language circuits.

 

                                                                                                                                                       

1 Pulvermüller, F., & Fadiga, L. (2010). Active perception: Sensorimotor circuits as a cortical basis for language. Nature Reviews Neuroscience, 11(5), 351-360.

2 Pulvermüller, F., & Berthier, M. L. (2008). Aphasia therapy on a neuroscience basis. Aphasiology, 22(6), 563-599.

3 Berthier, M. L., & Pulvermüller, F. (2011). Neuroscience insights improve neurorehabilitation of post-stroke aphasia. Nature Reviews Neurology, 7(2), 86-97.

4 Pulvermüller, F., Neininger, B., Elbert, T., Mohr, B., Rockstroh, B., Koebbel, P., & Taub, E. (2001). Constraint-induced therapy of chronic aphasia following stroke. Stroke, 32(7), 1621-1626.

5 Berthier, M. L., Green, C., Lara, J. P., Higueras, C., Barbancho, M. A., Davila, G., & Pulvermuller, F. (2009). Memantine and constraint-induced aphasia therapy in chronic poststroke aphasia. Annals of Neurology, 65(5), 577-585.

6 DiFrancesco, S., Pulvermüller, F., & Mohr, B. (2012). Intensive language action therapy: the methods. Aphasiology, 26(11), 1317-1351.