Maxim Gureev

Education and Degrees

2020

Candidate of Sciences* (PhD)
Institute of Physiologically Active Substances of the Russian Academy of Sciences

2011

Degree in Chemical Technology of Organic Nitrogen Compounds
St Petersburg State Institute of Technology

* Candidate of Sciences
According to the International Standard Classification of Education (ISCED) 2011, Candidate of Sciences belongs to ISCED level 8 - "doctoral or equivalent", together with PhD, DPhil, D.Lit, D.Sc, LL.D, Doctorate or similar. Candidate of Sciences allows its holders to reach the level of the Associate Professor.

Professional Interests

High-Performance Computing (HPC)molecular modeling virtual screening Computer aided drug design transmembrane proteins molecular dynamics metadynamics

Grants

Supervision:
- Russian Foundation for Basic Research, project no. 14-04-31684 mol_a «The development of multitarget small molecule inhibitors of Mdm2 and Mdm4 using fragment-based drug design techniques», 2014-2015.

Executor:

- Grant RSF No. №23-75-10096 «Mechanisms of functioning of transcription factors Oct4, Sox2, Nanog and Pcbp1 in the pluripotency dynamics», 2023-present.
- Grant RSF No. 19-73-10150 «Multitarget rational design of small molecule anti-cancer compounds», 2019-2022.
- Grant RFBR № № 20-04-60038 "Design and search of S protein SARS-CoV-2 inhibitor" 2020-2021 гг.
- Grant RFBR № № 20-33-70250 "Complex study of efflux proteins as platform for design of multitarget drugs" 2019-2020
- Grant RSF No. 16-13-10358 "Directional construction of selective inducers of apoptosis for the treatment of oncological diseases", 2016-2018, 2019-2020.

WO2023180387 (A1) - SMALL-MOLECULE INHIBITORS TARGETING THE BOB1/OCT1 INTERFACE

The present invention relates to compounds or pharmaceutically acceptable salts and/or solvates thereof. The invention further relates to the use of the compounds of the invention as immunomodulators. The invention further relates to the compounds of the invention for use in the treatment of autoimmune diseases, transplanted organ rejection, graft-versus-host-disease and BOB1-related diseases.

Employment history

Apr. 2012- Aug. 2021 - SPbSTI(TU) postgraduate student (till 2016), junior res. (till 2018), researcher (till 2020), Research Laboratory "Molecular Pharmacology";

Sep. 2017-Dec. 2019 - ITMO university, Assistant, Bioinformatics Laboratory;

Aug. 2020 - Dec. 2023 - Sirius university, ns, Bioinformatics Laboratory;

Feb. 2017-Jan. 2024 - I.M. Sechenov First Moscow State Medical University, junior res. (till 2018), researcher (till 2020), senior res. (2024)., center of bio- and chemoinformatics, Institute of Biodesign and Modeling of Complex Systems.

sep. 2023 - present. - INC RAS, Laboratory of Molecular Biology of Stem Cells, Russian Academy of Sciences.

dec. 2023 - present. - National Research University Higher School of Economics, Scientific and Education Laboratory of Bio- and Chemoinformatics