Tag "coronavirus"

A team of researchers, including scientists of the HSE Faculty of Biology and Biotechnology, have analysed the evolutionary path of the coronavirus from the Wuhan variant to Omicron. Their findings indicate that many genomic mutations in SARS-CoV-2 are shaped by processes occurring in the intestines and lungs, where the virus acquires the ability to evade the inhibitory effects of microRNA molecules. The study findings have been published in the Journal of Medical Virology.

HSE researchers, in collaboration with their colleagues from Skoltech and the Central Research Institute for Epidemiology, have uncovered the mechanisms behind the emergence of new and dangerous coronavirus variants, such as Alpha, Delta, Omicron, and others. They have discovered that the likelihood of a substitution occurring at a specific site of the SARS-CoV-2 genome is dependent on concordant substitutions occurring at other sites. This explains why new and more contagious variants of the virus can emerge unexpectedly and differ significantly from those that were previously circulating. The study’s findings have been published in eLife.

Sergey A. Aksenov,Deputy Director of MIEM and Associate Professor at the School of Applied Mathematics, explains what mathematical modelling is about and what projects HSE MIEM research teams have been working on recently, particularly in relation to COVID-19.

Russian researchers have developed a strategy to create a cheap and rapid COVID-19 test based on isothermal amplification. According to their publication in Applied Biochemistry and Microbiology, use of this strategy will make it possible to create universal test systems for any of the COVID-19 variants.

HSE social and political analysts have established which value models and circumstances promote support for restrictive government policies aimed at combatting the coronavirus pandemic. The research is published in Plos One.

Researchers from the HSE Faculty of Economic Sciences have proposed a mathematical model that describes the course of the COVID-19 pandemic, taking into account the restrictions applied in different countries. The model will help governments make reasonable and timely decisions on introducing or lifting restrictions. The paper was published in Eurasian Economic Review.