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Tag "Linear classifiers"

HSE Laboratory Research Fellow Anton Zhiyanov Successfully Defends PhD Thesis in Computer Science

A linear classifier distinguishing between homogeneous and heterogeneous cleavage at the 5′ end of the 3′ arm based on the nucleotide sequence in the region of the microRNA cleavage position
On 27 February 2026, Anton P. Zhiyanov, a research fellow at the Laboratory of Molecular Physiology, Faculty of Biology and Biotechnology, HSE University, successfully defended his dissertation “Methods for Evaluating the Quality of Linear Classifiers for microRNA Sequence Analysis” before the HSE University Dissertation Council in Computer Science. The thesis develops an axiomatic framework for comparing classification metrics, proposes new statistical tools for verifying linear classifiers, and applies them to the bioinformatics problem of microRNA isoform prediction. By its decision of 26 March 2026, the Dissertation Council conferred the sought-after degree on Anton.

HSE Researchers Develop Method to Verify Reliability of Computer-Based Cancer Recurrence Prediction

A "non-random classifier" based on IGFBP6 and ELOVL5 gene expression.
Research by a collaborative team from HSE University's Faculty of Biology and Biotechnology, Moscow State University, and the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences has been officially published in the international journal Stat. The study addresses a critical challenge in biomedicine: determining whether machine learning algorithms identify genuine biological patterns or merely overfit to random noise in data.