On December 4, 2025, Evgeny Knyazev, Head of the Molecular Physiology Laboratory at HSE University, delivered a presentation titled "Modeling Preeclampsia and Inflammatory Bowel Diseases Using Placenta-on-a-Chip and Intestine-on-a-Chip Models" at the III International Forum of Genomic and Biomedical Technologies "From Birth to Active Longevity" in Surgut.
A research article by a collaborative team from the Molecular Physiology Laboratory at HSE University and the V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology has been published in a leading medical journal. The study presents the first comparative analysis of immune-associated gene expression in classical blood monocytes from women with preeclampsia compared to physiological pregnancy.
Researchers at the Molecular Physiology Laboratory of HSE University presented results of a multidisciplinary investigation into preeclampsia, correlating single-cell sequencing data from placental tissue in early-onset preeclampsia with experimental hypoxia induction in cell models. For the first time, gene expression profiles in diseased placental samples were directly compared to the molecular response of trophoblasts subjected to chemical hypoxia induction using a novel oxyquinoline derivative.
