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Research of self-assembly of viral capsids scenarios and modeling algorithmic behavior of proteins

Student: Podobin Aleksandr

Supervisor: Alexander Makhiboroda

Faculty: HSE Tikhonov Moscow Institute of Electronics and Mathematics (MIEM HSE)

Educational Programme: Mathematical Methods of Natural Sciences and Computer Technologies (Master)

Final Grade: 8

Year of Graduation: 2016

The work is devoted to the study of the phenomenon of the self-assembly of virus capsids, relevant to the development of theoretical biology, medical practices and nanotechnology. In the course of the work was made a review of the architecture of viral particles by self-assembly of experimental observations scenarios of viral capsids and modeling self-assembly processes. In the course of the work was concluded on the incompleteness of modern ideas about the principles of management and coordination of self-assembly processes and the requirements to the mathematical tools to describe the distributed management processes. It is the choice of mathematical tools that support algorithmic description of systems with distributed management, formulated the concept of security locks as the media control components algorithmic systems with distributed control. Examples of the construction of algorithmic processes modeling important pieces of self-assembly of viral capsids.

Full text (added May 25, 2016)

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