Tag "International Laboratory of Microphysiological Systems"

A press release has been released on the HSE website (https://www.hse.ru/news/science/1152167635.html) based on an article about the unique properties of miR-93-5p microRNA (published in the journal PeerJ https://peerj.com/articles/20642/). HSE researchers have discovered an atypical behavior of oncogenic miR-93-5p microRNA in prostate cancer. It turned out that its various isoforms do not change the spectrum of target genes, but rather enhance each other's effects.

Tests of the modern 3D FloTrix MicroSpin bioreactor from Cytoniche, designed for the cultivation of adhesive cells using microcarrier technology, have begun at the international Laboratory of Microphysiological Systems

miR-93-5p microRNA in prostate cancer retains a similar set of targets even with the formation of 5’ isoforms. This indicates the stability of its regulatory function to structural variations.