Sergey Nikulin

Publications²⁴

• Article Nikulin S., Razumovskaya A., Poloznikov A., Zakharova G., Alekseev B., Tonevitsky A. ELOVL5 and IGFBP6 genes modulate sensitivity of breast cancer cells to ferroptosis // Frontiers in Molecular Biosciences. 2023. Vol. 10. Article 1075704. doi
• Article Poloznikov A., Nikulin S., Hushpulian D. M., Khristichenko A. Y., Osipyants A. I., Asachenko A. F., Shurupova O. V., Savin S. S., Lee S. H., Gaisina I. N., Thatcher G. R., Narciso A., Chang E. P., Kazakov S. V., Krucher N., Tishkov V. I., Thomas B., Gazaryan I. G. Structure–Activity Relationships and Transcriptomic Analysis of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors // Antioxidants. 2022. Vol. 11. No. 2. Article 220. doi
• Article Poloznikov A., Nikulin S., Bolotina L., Kachmazov A., Raigorodskaya M., Kudryavtseva A., Bakhtogarimov I., Rodin S., Gaisina I., Topchiy M., Asachenko A., Novosad V., Tonevitsky A., Alekseev B. 9-ING-41, a Small Molecule Inhibitor of GSK-3β, Potentiates the Effects of Chemotherapy on Colorectal Cancer Cells // Frontiers in Pharmacology. 2021. Vol. 12. Article 777114. doi
• Article Ahuja M., Ammal Kaidery N., Attucks O. C., McDade E., Hushpulian D. M., Gaisin A., Gaisina I., Ahn Y. H., Nikulin S., Poloznikov A., Gazaryan I. G., Yamamoto M., Matsumoto M., Igarashi K., Sharma S. M., Thomas B. Bach1 derepression is neuroprotective in a mouse model of Parkinson’s disease // Proceedings of the National Academy of Sciences of the United States of America. 2021. Vol. 118. No. 45. Article e2111643118. doi
• Article Nersisyan S., Novosad V., Engibaryan N., Ushkaryov Y., Nikulin S., Tonevitsky A. ECM–Receptor Regulatory Network and Its Prognostic Role in Colorectal Cancer // Frontiers in Genetics. 2021. Vol. 12. Article 782699. doi
• Article Nikulin S., Zakharova G., Poloznikov A., Raigorodskaya M., Wicklein D., Schumacher U., Nersisyan S., Bergquist J., Bakalkin G., Astakhova L., Tonevitsky A. Effect of the Expression of ELOVL5 and IGFBP6 Genes on the Metastatic Potential of Breast Cancer Cells // Frontiers in Genetics. 2021. Vol. 12. Article 662843. doi
• Article Poloznikov A., Nersisyan S., Hushpulian D., Kazakov E., Tonevitsky A., Kazakov S., Vechorko V., Nikulin S., Makarova J., Gazaryan I. G. HIF Prolyl Hydroxylase Inhibitors for COVID-19 Treatment: Pros and Cons // Frontiers in Pharmacology. 2021. Vol. 11. Article 621054. doi
• Article Хушпульян Д. М., Никулин С. В., Христиченко А. Ю., Полозников А. А., Газарян И. Г., Чубарь Т. А. Гены «быстрого» отклика при действии ингибиторов HIF пролилгидроксилазы // Вестник Московского университета. Серия 2: Химия. 2021. Т. 62. № 3. С. 213-222. doi
• Article Разумовская А. В., Никулин С. В., Алексеев Б. Я., Горбунов А. Н., Вацуро И. М., Ковалев В. В., Полозников А. А. ИССЛЕДОВАНИЕ ТОКСИЧНОСТИ КАЛИКС[4]- И [6]-АРЕНОВ И ИХ СУЛЬФАТИРОВАННЫХ ПРОИЗВОДНЫХ В ДВУМЕРНОЙ И ТРЕХМЕРНОЙ КУЛЬТУРЕ КЛЕТОЧНОЙ ЛИНИИ КОЛОРЕКТАЛЬНОЙ АДЕНОКАРЦИНОМЫ // Биотехнология. 2021. Т. 37. № 1. С. 87-94. doi
• Article Nikulin S., Alekseev B. Y., Sergeeva N., Karalkin P., Nezhurina E., Kirsanova V., Sviridova I., Akhmedova S., Volchenko N., Bolotina L., Osipyants A., Hushpulian D., Topchiy M., Asachenko A., Koval A., Shcherbo D., Kiselev V., Mikhaylenko D., Schumacher U., Poloznikov A. Breast cancer organoid model allowed to reveal potentially beneficial combinations of 3,3′-diindolylmethane and chemotherapy drugs // Biochimie. 2020. Vol. 179. P. 217-227. doi
• Article Maltseva D., Raygorodskaya М., Knyazev E., Zgoda V., Tikhonova O., Zaidi S., Nikulin S., Baranova A., Turchinovich A., Rodin S., Tonevitsky A. Knockdown of the α5 Laminin Chain Affects Differentiation of Colorectal Cancer Cells and Their Sensitivity to Chemotherapy // Biochimie. 2020. Vol. 174. P. 107-116. doi
• Article Savyuk M., Krivonosov M., Mishchenko T., Gazaryan I. G., Ivanchenko M., Khristichenko A., Poloznikov A., Hushpulian D., Nikulin S., Tonevitsky E., Abuzarova G., Mitroshina E., Vedunova M. Neuroprotective Effect of HIF Prolyl Hydroxylase Inhibition in an In Vitro Hypoxia Model // Antioxidants. 2020. Vol. 9. No. 8. Article 662. doi
• Article Мальцева Д. В., Шкурников М. Ю., Нерсисян С. А., Никулин С. В., Курносов А. А., Райгородская М. П., Осипьянц А. И., Тоневицкий Е. А. Гипоксия усиливает трансцитоз в энтероцитах кишечника // Вестник Российского государственного медицинского университета. 2020. № 4. С. 62-69. doi
• Article Poloznikov A., Nikulin S., Zakhariants A. A., Khristichenko A. Y., Hushpulian D. M., Gazizov I. N., Tishkov V. I., Gazaryan I. G. "Branched Tail" Oxyquinoline Inhibitors of HIF Prolyl Hydroxylase: Early Evaluation of Toxicity and Metabolism Using Liver-on-a-chip // Drug Metabolism Letters. 2019. Vol. 13. No. 1. P. 45-52. doi
• Article Nikulin S., Knyazev E., Gerasimenko T., Gazizov I., Petrov V., Kindeeva O., Sakharov D. Application of impedance spectroscopy for analysis of BeWo clone b30 human choriocarcinoma cell line // Placenta. 2019. Vol. 83. P. e21. doi
• Article Yu.A. Makarova, Poloznikov A.A., Nikulin S.V., Raigorodskaya M., Fomicheva K. A., Zakharova G., Alekseev B. Y. Changes in the Metastatic Properties of MDA-MB-231 Cells after IGFBP6 Gene Knockdown Is Associated with Increased Expression of miRNA Genes Controlling INSR, IGF1R, and CCND1 Genes // Bulletin of Experimental Biology and Medicine. 2019. Vol. 166. No. 5. P. 641-645. doi
• Article Gerasimenko T., Nikulin S., Zakharova G., Poloznikov A., Petrov V., Baranova A., Tonevitsky A. Impedance Spectroscopy as a Tool for Monitoring Performance in 3D Models of Epithelial Tissues // Frontiers in Bioengineering and Biotechnology. 2019. Vol. 7. P. 474. doi
• Article Shkurnikov M., Nikulin S., Nersisyan S., Poloznikov A., Zaidi S., Baranova A., Schumacher U., Wicklein D., Tonevitsky A. LAMA4-Regulating miR-4274 and Its Host Gene SORCS2 Play a Role in IGFBP6-Dependent Effects on Phenotype of Basal-Like Breast Cancer // Frontiers in Molecular Biosciences. 2019. Vol. 6. No. 122. P. 1-7. doi
• Article Shkurnikov M., Nikulin S., Nersisyan S., Poloznikov A., Tonevitsky A. LAMA4-Regulating miR-4274 and Its Host Gene SORCS2 Play a Role in IGFBP6-Dependent Effects on Phenotype of Basal-Like Breast Cancer // Frontiers in Molecular Biosciences. 2019. Vol. 6. No. 8. P. 122. doi
• Article Sakharov D., Maltseva D., Knyazev E., Nikulin S., Poloznikov A., Shilin S., Baranova A., Tsypina I., Tonevitsky A. Towards embedding Caco-2 model of gut interface in a microfluidic device to enable multi-organ models for systems biology // BMC Systems Biology. 2019. Vol. 13. No. 19. P. 3-11. doi
• Article Knyazev E. N., Nikulin S. V., Khristichenko A. Y., Gerasimenko T. N., Kindeeva O. V., Petrov V. A., Belyakova G. A., Maltseva D. V. Transport and toxicity of 5-fluorouracil, doxorubicin, and cyclophosphamide in in vitro placental barrier model based on BeWo b30 cells // Russian Chemical Bulletin. 2019. Vol. 68. No. 12. P. 2344-2349. doi
• Article Gaisina I. N., Lee S. H., Kaidery N. A., Aissa M. B., Ahuja M., Smirnova N. N., Wakade S., Gaisin A., Bourassa M. W., Ratan R. R., Nikulin S., Poloznikov A., Thomas B., Thatcher G. R., Gazaryan I. Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors // ACS Chemical Neuroscience. 2018. Vol. 9. No. 5. P. 894-900. doi
• Article Poloznikov A., Gazaryan I. G., Shkurnikov M., Nikulin S., Drapkina O., Baranova A., Tonevitsky A. In vitro and in silico liver models: Current trends, challenges and opportunities // ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION. 2018. Vol. 35. No. 3. P. 397-412. doi
• Article Ivashchenko D. V., Rudik A. V., Poloznikov A., Nikulin S., Smirnov V. V., Tonevitsky A., Bryun E. A., Sychev D. A. Which cytochrome P450 metabolizes phenazepam? Step by step in silico, in vitro, and in vivo studies // Drug Metabolism and Personalized Therapy. 2018. Vol. 33. No. 2. P. 65-73. doi